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Benign Prostatic Hyperplasia
The prostate is a small gland below the bladder that surrounds the urethra, the tube that carries urine. As men age, it often enlarges, compressing the urethra and making urination more difficult. This condition, called BPH, affects millions of men worldwide.
Today’s treatments range from surgically removing excess prostate tissue, using heat to shrink or destroy tissue, to placing implants that open the blocked area. While effective for some men, these approaches may also carry risks of bleeding, pain, catheterization, or unintended effects on urinary or sexual function.

Men hesitate to seek treatment, worried about recovery, changes to sexual function, and the possibility of lasting urinary problems.
Targeted precision
ALPFA Pulsed Field Ablation (PFA) uses targeted electrical energy - without heat - to remodel prostate tissue and restore elasticity. This tissue-selective mechanism is distinct from traditional BPH treatments.

Targeted electrical energy. No heat.
Tissue-selective treatment of the prostate.
No incisions. No punctures.
Uses the body’s natural anatomy.
Designed to reduce risk.
No heat means a lower risk of complications.
Transforming BPH Ablation
Precisely engineered.
The ALPFA GRAIL System is a purpose-built platform integrating energy delivery, catheter design, and software control to enable precise ablation in complex anatomy.